Cécile Brocard Selected Research

Spinal Cord Injuries (Spinal Cord Injury)

1/2023	Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial.
12/2019	Calpain fosters the hyperexcitability of motoneurons after spinal cord injury and leads to spasticity.
1/2018	Activation of 5-HT2A Receptors Restores KCC2 Function and Reduces Neuropathic Pain after Spinal Cord Injury.
4/2016	Cleavage of Na(+) channels by calpain increases persistent Na(+) current and promotes spasticity after spinal cord injury.
1/2011	Chapter 1--importance of chloride homeostasis in the operation of rhythmic motor networks.
3/2010	Differential plasticity of the GABAergic and glycinergic synaptic transmission to rat lumbar motoneurons after spinal cord injury.
3/2010	Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury.

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Cécile Brocard Research Topics

Disease

7	Spinal Cord Injuries (Spinal Cord Injury) 01/2023 - 03/2010
2	Pain (Aches) 01/2023 - 01/2013
1	Spasm (Spasms) 01/2023
1	Neurodevelopmental Disorders 01/2022
1	Hypoxia (Hypoxemia) 01/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021
1	Abnormal Reflex (Hyperreflexia) 01/2018
1	Neuralgia (Stump Neuralgia) 01/2018
1	Hyperalgesia 01/2018
1	Mental Disorders (Mental Disorder) 01/2013
1	Nervous System Diseases (Neurological Disorders) 01/2013
1	Starvation 12/2005

Drug/Important Bio-Agent (IBA)

3	gamma-Aminobutyric Acid (GABA)IBA 01/2022 - 03/2010
3	ChloridesIBA 01/2022 - 01/2013
3	CalpainIBA 01/2022 - 04/2016
3	Potassium Chloride FDA LinkGeneric 12/2019 - 03/2010
2	K Cl- CotransportersIBA 01/2022 - 03/2010
2	SodiumIBA 12/2019 - 04/2016
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2011 - 03/2010
1	Riluzole FDA LinkGeneric 01/2023
1	CatecholaminesIBA 01/2022
1	Dopamine (Intropin)FDA LinkGeneric 01/2022
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2022
1	Glycine Receptors (Glycine Receptor)IBA 01/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2022
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022
1	Superoxide Dismutase-1IBA 01/2021
1	isonitrosoacetophenoneIBA 12/2019
1	Analgesics (Analgesic Drugs)IBA 01/2018
1	((dihydroindenyl)oxy)alkanoic acidIBA 01/2018
1	(4- bromo- 3,6- dimethoxybenzocyclobuten- 1- yl)methylamineIBA 01/2013
1	GABA-A Receptors (GABA(A) Receptor)IBA 03/2010
1	Protein Phosphatase 1IBA 12/2005
1	Glucose (Dextrose)FDA LinkGeneric 12/2005
1	Transcription Factors (Transcription Factor)IBA 12/2005

Therapy/Procedure

1	Spinal Injections 01/2018